Chronic neutrophilic leukaemia
نویسندگان
چکیده
منابع مشابه
Chronic neutrophilic leukaemia.
Chronic neutrophilic leukaemia (CNL) is a rare type of myeloproliferative neoplasm (MPN) characterised by sustained leucocytosis (≥25×10(9)/L) with neoplastic proliferation of neutrophilic granulocytes in blood and bone marrow. In contrast to chronic myeloid leukaemia, the disease primarily involves neutrophilic lineage with persistent proliferation of mature forms of neutrophils. No consistent...
متن کاملEvidence of clonality in chronic neutrophilic leukaemia.
BACKGROUND Chronic neutrophilic leukaemia (CNL) is a rare myeloproliferative disorder of elderly patients characterised by sustained neutrophilia and splenomegaly. The diagnosis of CNL requires the exclusion of BCR/ABL positive chronic myelogenous leukaemia (CML) and of leukaemoid reactions (LRs). The differentiation between CNL and LR is problematic because both conditions share similar morpho...
متن کاملChronic neutrophilic leukaemia with enlarged lymph nodes and lysozyme deficiency.
A further case of chronic neutrophilic leukaemia is reported and compared to fourteen previously reported cases. The presence of enlarged lymph nodes as the first clinical sign and the existence of a relative lysozyme deficiency of the granulocytes were striking features.
متن کاملChronic neutrophilic leukaemia: 14 new cases of an uncommon myeloproliferative disease.
BACKGROUND Chronic neutrophilic leukaemia (CNL) is a distinct BCR/ABL negative myeloproliferative disorder of elderly patients characterised by sustained neutrophilia and splenomegaly. The bone marrow shows expansion of neutrophilic granulopoiesis, without excess of myeloblasts. To date, only 129 cases of CNL have been reported in the literature. AIMS To report the findings from a large group...
متن کاملElectron microscopic findings of parallel tubular granules in a case of chronic neutrophilic leukaemia.
A case of chronic neutrophilic leukaemia (CNL) is reported. The diagnosis was based on leucocytosis with mature neutrophils, a raised leucocyte alkaline phosphatase score, negative Philadelphia chromosome, and extensive infiltration of neutrophils in various differentiation stages into the bone marrow. When viewed by light microscopy, these neutrophils were almost normal in appearance, except f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2015
ISSN: 0021-9746,1472-4146
DOI: 10.1136/jclinpath-2015-203060